Constructing a differential game model of energy flow in chemosynthetic biota

Simulating microbial communities to optimize energy flow and predict community behavior effectively.

Innovating Microbial Community Modeling

We develop advanced differential game models to simulate energy flow dynamics in synthetic microbial communities, integrating experimental data for validation and refinement.

Clusters of variously shaped and colored microbial colonies appear on a dark surface. The textures are varied, with some colonies smooth and others more granular. The colors range from bright green to light yellow and brown, creating a contrast against the dark background.
Clusters of variously shaped and colored microbial colonies appear on a dark surface. The textures are varied, with some colonies smooth and others more granular. The colors range from bright green to light yellow and brown, creating a contrast against the dark background.
Colonies of microorganisms are scattered across a petri dish. The colonies vary in size but are mostly small and round. They create a dense clustering toward the center with more scattered formations around the edges.
Colonies of microorganisms are scattered across a petri dish. The colonies vary in size but are mostly small and round. They create a dense clustering toward the center with more scattered formations around the edges.

Constructadifferentialgamemodeltosimulateenergyflowdynamicsinsyntheticmicrobialcommunities,incorporatingvariablessuchasnutrientavailability,metabolicrates,andinterspeciesinteractions.

ModelDevelopment

A petri dish containing various colonies of bacteria and fungi, showcasing diverse shapes, sizes, and colors. The colonies are growing on a nutrient agar medium with a grid pattern beneath them. Some colonies are circular and smooth, while others have fringed or filamentous edges. The dish is viewed from above, displaying a layer of translucent medium and different colony morphologies.
A petri dish containing various colonies of bacteria and fungi, showcasing diverse shapes, sizes, and colors. The colonies are growing on a nutrient agar medium with a grid pattern beneath them. Some colonies are circular and smooth, while others have fringed or filamentous edges. The dish is viewed from above, displaying a layer of translucent medium and different colony morphologies.

DataIntegration

Useexperimentaldatafrommicrobialcommunitiestoparameterizeanvalidatethemodel.

A cluster of orange, cylindrical microorganisms or bacteria against a black background, appearing three-dimensional with shadows and depth.
A cluster of orange, cylindrical microorganisms or bacteria against a black background, appearing three-dimensional with shadows and depth.

SimulationandAnalysis

Runsimulationstoanalyzeenergyflowpatterns,communitystability,andefficiency,andcompareresultswithexperimentalobservations.

Simulation

Modeling energy dynamics in microbial communities effectively.

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